Trending Stack: Semaglutide + MOTS-c for Enhanced Fat Loss

Michelle LopezJanuary 23, 2026 at 3:16 PM3 views

Seeing a lot of discussion around combining Semaglutide with MOTS-c lately. The synergy makes sense - Semaglutide handles appetite suppression while MOTS-c targets mitochondrial function and metabolic efficiency. Key benefits reported: - Enhanced fat oxidation - Improved energy levels - Better metabolic markers - Reduced muscle loss during calorie deficit Important: These are separate mechanisms, not overlapping GLP-1s, so stacking is considered safe by most researchers. Source: https://pubmed.ncbi.nlm.nih.gov/ Anyone here running this combination? What dosages are working for you?

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