Retatrutide vs Tirzepatide: Real-World Comparison

Nevada EvansJanuary 20, 2026 at 10:17 PM523 views

After 12 weeks on Tirzepatide and now 8 weeks into Retatrutide, here's my honest comparison: Tirzepatide (12 weeks): • Lost 28 lbs • Minimal side effects • Appetite suppression was strong • Energy levels stayed consistent Retatrutide (8 weeks so far): • Lost 22 lbs already (faster rate!) • Stronger appetite suppression • More energy/thermogenic effect • Slightly more nausea first 2 weeks Bottom line: Retatrutide seems more potent for fat loss, but Tirzepatide might be better if you're sensitive to side effects. Research: [Retatrutide Phase 2 Trial Results](https://pubmed.ncbi.nlm.nih.gov/37000000/) - 24% body weight reduction at 48 weeks.

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